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1. Something or someone that one vehemently dislikes
2. A formal curse by a pope or a council of the Church, excommunicating a person or denouncing a doctrine
1. The villainous Thanos, with his plan to eliminate half of the universe's population, was anathema to the Avengers.
2. Batman considered the use of firearms anathema, as it went against his core principles.
3. In 'The Godfather', the idea of betrayal was anathema to the Corleone family's code of honor.
4. In ancient times, promoting ideas that contradicted religious teachings could result in one being declared anathema by the church.