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1. Of fundamental importance; principal
2. A leading dignitary of the Roman Catholic Church
1. Respecting others' opinions is a cardinal rule in a democratic society.
2. Batman often wrestles with cardinal choices that can determine the fate of Gotham.
3. The cardinal was appointed by the Pope to oversee the new initiatives in community outreach.
4. Tony Stark's cardinal principle is to protect the world from any form of danger, no matter the personal cost.