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1. A feeling of fear or anxiety about something that may happen
2. A trembling movement
1. Peter Parker felt a sense of trepidation as he faced the new villain threatening New York City.
2. Bruce Wayne's trepidation was palpable when he discovered the Joker's nefarious plot.
3. As Nobita opened Doraemon's gadget box, he did so with a mix of excitement and trepidation, unsure of what might come out.
4. When Frodo Baggins prepared to leave the Shire, he did so with trepidation, knowing the perilous journey that lay ahead.